Centre for Cardiovascular Medicine and Devices, William Harvey Research Institute, 560754Queen Mary University of London, United Kingdom. Barts Interventional Group, Barts Heart Centre, Barts Health NHS Trust, London, United Kingdom. Barts Cardiovascular Clinical Trials Unit, 560754Queen Mary University of London, London, United Kingdom. Department of Pharmacy, 560754Barts Heart Centre, London, United Kingdom. Department of Nephrology, 9744Barts Health NHS Trust, London, United Kingdom. Department of Health Policy, 4905London School of Economics, London, United Kingdom.